grad-biophysics

The doctor of philosophy degree with a major in biophysics is an interdepartmental offering under the supervision of the Biophysics Graduate Degree Program. The biophysics degree is intended for those who wish to emphasize physical principles and methods in solving biological problems. By necessity, the interdisciplinary nature of biophysics generates interaction among, and expands the boundaries of, traditional areas of science. Persons with strong training in biophysics can be expected to be major innovators and contributors in research and applied technology. Biophysics graduates pursue careers in academic, industrial, and government research, and in teaching and administration.

The Biophysics Program consists of approximately 56 faculty members from 14 departments that span four colleges within the university. State-of-the-art facilities are available within the Biophysics Program for research in x-ray crystallography, nuclear magnetic-resonance spectroscopy, electron resonance spectroscopy, fluorescence spectroscopy, microscopy and imaging, and computational chemistry. Graduate students in biophysics can choose from an expansive range of research topics including, but not limited to, biomolecular structure and function interactions, protein engineering and biotechnology, virus structure and function, enzyme catalysis and kinetics, membranes, neurochemistry, and electrophysiology.

The program is flexible in its formal course requirements and emphasizes excellence in research. The candidate is encouraged to begin research as quickly as possible, since it is research experience that brings focus and meaning to classroom studies, and research progress that empowers critical judgment and self-confidence for independent work. To enhance self-confidence, students are expected to participate in weekly seminars and to present a seminar.

Financial assistance is available to support qualified graduate students throughout their graduate studies. Types of graduate appointments that may be awarded include research assistantships, fellowships, and traineeships. The stipends awarded provide financial support to students during their graduate work, permitting them to devote their efforts to coursework and research. In recognition of the leadership provided by scientists and researchers at University of Wisconsin–Madison, the National Institutes of Health (NIH) have funded a predoctoral training grant in molecular biophysics for the past consecutive 20 years.

For more information, see the Biophysics Handbook.

Please consult the table below for key information about this degree program’s admissions requirements. The program may have more detailed admissions requirements, which can be found below the table or on the program’s website.

Graduate admissions is a two-step process between academic programs and the Graduate School. Applicants must meet the minimum requirements of the Graduate School as well as the program(s). Once you have researched the graduate program(s) you are interested in, apply online.

Fall Deadline December 1
Spring Deadline The program does not admit in the spring.
Summer Deadline The program does not admit in the summer.
GRE (Graduate Record Examinations) Not required but may be considered if available.
English Proficiency Test Every applicant whose native language is not English or whose undergraduate instruction was not in English must provide an English proficiency test score and meet the Graduate School minimum requirements (https://grad.wisc.edu/apply/requirements/#english-proficiency).
Other Test(s) (e.g., GMAT, MCAT) n/a
Letters of Recommendation Required 3

Undergraduate preparation for the Biophysics Program can vary widely and will be evaluated by the admissions committee on an individual basis. Most applicants have taken courses in general, organic, and physical chemistry; introductory physics; cell and/or molecular biology; calculus through differential equations; and computer sciences. Students can generally make up any deficiencies in their undergraduate background within the first year of graduate study through a broad and flexible course curriculum. The normal undergraduate course prerequisites are:

  • two semesters of physics with calculus
  • two semesters of calculus
  • two semesters of organic chemistry
  • one semester of physical chemistry
  • one semester of computer sciences
  • one semester of statistics
  • introduction to biology

Exceptions to these requirements may be granted for incoming biophysics graduate students who otherwise have strong undergraduate training in physics, mathematics, computer sciences, biology, chemistry, or other fields related to biophysics. In such cases, each missing required course will be counted as a deficiency that the student must correct by obtaining a passing grade in an equivalent undergraduate or graduate course taken within the first two years of graduate study.

In addition, it is recommended for entering graduate students to have taken undergraduate courses in general biochemistry; general genetics and/or molecular biology; and biophysical chemistry. Students who have not taken courses in these subjects will be expected to do so as part of their formal graduate coursework.

Admission to the biophysics Ph.D. program is highly competitive. A committee of biophysics faculty trainers reviews each application and invites selected students for personal interviews in February. Outstanding international students will be offered video-conferencing interviews with members of the admissions committee. Final admissions decisions are made after all interviews are completed. An application for admission consists of:

1. A resume or CV

2. A personal statement that discusses a candidate's reasoning for pursuing a biophysics Ph.D. What initially drew you to the field? How will earning a Ph.D. help you accomplish your goals?

3. An official transcript of coursework from all undergraduate institutions attended

4. Three or more letters of recommendation

5. A report, if submitting, from the Educational Testing Service of scores received on the GRE General Test

6. A report, if appropriate, of scores received on the TOEFL English language proficiency exam or an appropriate alternative (IELTS, MELAB)

The admissions committee highly weighs the personal statement and letters of recommendation when reviewing applicants. GPA values are evaluated to ensure they meet minimum graduate school requirements.

Graduate School Resources

Resources to help you afford graduate study might include assistantships, fellowships, traineeships, and financial aid. Further funding information is available from the Graduate School. Be sure to check with your program for individual policies and restrictions related to funding.

Program Resources

The Biophysics Graduate Degree Program offers stipends in the form of traineeships or research assistantships to all Ph.D. candidates, and assists those with outstanding records in competing for University and national awards (fellowships). The program guarantees a full stipend ($30,000 for 2021–22) for all its Ph.D. candidates who remain in good standing in the program. In addition to the stipend, all students receive tuition remission and are eligible for comprehensive health insurance.

Minimum Graduate School Requirements

Review the Graduate School minimum academic progress and degree requirements, in addition to the program requirements listed below.

Major Requirements

MODE OF INSTRUCTION

Face to Face Evening/Weekend Online Hybrid Accelerated
Yes No No No No

Mode of Instruction Definitions

Accelerated: Accelerated programs are offered at a fast pace that condenses the time to completion. Students are able to complete a program with minimal disruptions to careers and other commitments.

Evening/Weekend: ​Courses meet on the UW–Madison campus only in evenings and/or on weekends to accommodate typical business schedules.  Students have the advantages of face-to-face courses with the flexibility to keep work and other life commitments.

Face-to-Face: Courses typically meet during weekdays on the UW-Madison Campus.

Hybrid: These programs combine face-to-face and online learning formats.  Contact the program for more specific information.

Online: These programs are offered 100% online.  Some programs may require an on-campus orientation or residency experience, but the courses will be facilitated in an online format.

CURRICULAR REQUIREMENTS

Minimum Credit Requirement 51 credits
Minimum Residence Credit Requirement 32 credits
Minimum Graduate Coursework Requirement 26 credits must be graduate-level coursework. Details can be found in the Graduate School’s Minimum Graduate Coursework (50%) policy (https://policy.wisc.edu/library/UW-1244).
Overall Graduate GPA Requirement 3.00 GPA required.
This program follows the Graduate School's GPA Requirement policy (https://policy.wisc.edu/library/UW-1203).
Other Grade Requirements Credits are not counted from courses in which a grade of BC or below is obtained for the Biophysics core courses. In the event of an unsatisfactory grade, the student must repeat the course and obtain a grade of B or better if they want to count the class towards their Biophysics GPA and course requirements.
Assessments and Examinations Students are required to complete an oral preliminary exam. The oral exam should be completed no later than the end of the student’s third fall semester in the program. This exam consists of an oral defense of a written research proposal. The format of the research proposal is based on the format for an NIH F31 predoctoral grant application. If the student feels they need more time to complete the oral exam, they must request an extension from the Biophysics Office.
Language Requirements No language requirements.
Breadth Requirement No doctoral minor or Graduate/Professional certificate required.

Required Courses

Required by the time oral prelim is taken:
BIOCHEM/​CHEM  665 Biophysical Chemistry4
CHEM 668 Biophysical Spectroscopy 13
Biophysics Additional Courses 26
Students must take at least 2 additional classes from different categories from the following list of classes (alternative classes may be substituted with approval from the Biophysics Program Steering Committee):
Structure
Protein and Enzyme Structure and Function
Mechanisms of Action of Vitamins and Minerals
Organic Analysis
Introductory Quantum Chemistry
Purification and Characterization of Protein and Protein Complexes
Modeling
Chemical and Statistical Thermodynamics
Mathematical Methods for Systems Biology
Molecular Biology
Prokaryotic Molecular Biology
Eukaryotic Molecular Biology
Neuroscience
Cellular and Molecular Neuroscience
Spectroscopy/Microscopy
Microscopy of Life
Biomedical Optics and Biophotonics
Selected Topics in Physical Chemistry (Topic: Spectroscopy of Individual Molecules and Particles)
Advanced Topics (Topic: Advanced Topics in NMR)
Computational Courses
Bioinformatics for Biologists
Advanced Bioinformatics
Ethics Course1-3
Advanced Topics (Ethics) 3
Seminar Courses
Selected Topics in Macromolecular and Biophysical Chemistry
Students are required to participate in seminar courses for the duration of their studies. Initially, all students are required to enroll in CHEM/​BIOCHEM  872 (Topic: Macromolecular and Biophysical Chemistry) for both fall and spring semesters. Once a student has successfully achieved dissertator status, they are eligible to enroll in alternative seminars with permission from the program.
Speciality Courses
To fulfill the remainder of required credits, students can take specialty courses. It is recommended to take courses in areas such as biotechnology, computer science, electrical and computer engineering, molecular biology, or physics. Students should consult with their Thesis Advisor and thesis committee members about appropriate specialty courses to take pertaining to individual training goals.
Research Credits
Finally, all students are expected to register for 990 research credits every semester. These are the courses in which students will be conducting their independent research. First semester students will register for 990 research credits in the department of the Biophysics Program Chair. Once a thesis lab is chosen, these credits will be conducted in the thesis advisor's home department.
Total Credits51
1

Because CHEM 668 Biophysical Spectroscopy is only offered every other year, students will be advised upon joining the program in which semester they must complete the course. This course must be taken for 3 credits.

2

To meet the 6 credit minimum, all elective courses must be at least 2 credits. That means that students can, for example, take two 3-credit courses, three 2-credit courses, or one 2-credit and one 4-credit course to satisfy this requirement. The above list of courses have all been approved as elective courses by the Biophysics Steering Committee. If you are interested in a different course, in order for it to count as an elective course towards your Biophysics graduate degree, the course needs to be approved by the Steering Committee. Please email the coordinator at biophysics@bocklabs.wisc.edu a syllabus from the course and a short paragraph detailing why the class is relevant to your research.

3

Students are also required to take an ethics course that covers all of the items considered necessary by the NIH for ethical and professional scientific training. It is strongly recommended that students take the ethics course during their first year. The recommended ethics course is: BIOCHEM 729 Advanced Topics. The Biophysics Program also conducts a mandatory ethics refresher seminar for all students that is held at the end of every spring semester.

Graduate School Policies

The Graduate School’s Academic Policies and Procedures provide essential information regarding general university policies. Program authority to set degree policies beyond the minimum required by the Graduate School lies with the degree program faculty. Policies set by the academic degree program can be found below.

Major-Specific Policies

Prior Coursework

Graduate Work from Other Institutions

This program follows the Graduate School's policy for Satisfying Requirements with Prior Graduate Coursework from Other Institutions.

UW–Madison Undergraduate

This program follows the Graduate School's policy for Satisfying Requirements with Coursework from Undergraduate Career at UW–Madison.

UW–Madison University Special

This program follows the Graduate School's policy for Transfer from UW–Madison University Special Student Career at UW–Madison.

Probation

This program follows the Graduate School's Probation policy.

ADVISOR / COMMITTEE

All students are required to have an advisor by the end of their first semester in the program. Thesis committees must be formed at the end of a student's first year in the program. The committee consists of at least four other faculty members and the student's advisor and faculty must represent at least two different departments on campus. After gaining dissertator status, students are required to hold yearly progress report meetings with their committee until graduation.

CREDITS PER TERM ALLOWED

15 credits

Time Limits

This program follows the Graduate School's Time Limits policy.

grievances and appeals

These resources may be helpful in addressing your concerns:

Students should contact the department chair or program director with questions about grievances.

Other

Fall semester enrollment only. First semester, program-sponsored lab rotations lead to thesis lab selection and research assistantship through the thesis advisor.

Graduate School Resources

Take advantage of the Graduate School's professional development resources to build skills, thrive academically, and launch your career. 

  1. Articulates challenges, frontiers and limits with respect to theory, knowledge or practice within the field of study.
  2. Formulates ideas, concepts, designs, and/or techniques beyond the current boundaries of knowledge within the field of study.
  3. Creates research, scholarship or performance that makes a substantive contribution.
  4. Demonstrates breadth within their learning experiences.
  5. Communicates complex or ambiguous ideas in a clear and understandable manner.
  6. Evaluates the implications of the discipline to broader social concerns.
  7. Fosters ethical conduct and professional guidelines.

Faculty

Chair: Dr. Alessandro Senes (Biochemistry) Website

Paul Ahlquist (Oncology) Website

Tom Brunold (Chemistry) Website

Andrew Buller (Chemistry) Website

Mark Burkard (Medicine) Website

Judith Burstyn (Chemistry) Website

Briana Burton (Bacteriology) Website

Sam Butcher (Biochemistry) Website

Silvia Cavangerno (Chemistry) Website

Ed Chapman (Neuroscience) Website

Josh Coon (Chemistry) Website

Scott Coyle (Biochemistry) Website

Cindy Czajkowski (Neuroscience) Website

Katrina Forest (Bacteriology) Website

Brian Fox (Biochemistry) Website

Ying Ge (Cell and Regenerative Biology) Website

Sam Gellman (Chemistry) Website

Pupa Gilbert (Physics) Website

Randy Goldsmith (Chemistry) Website

Tim Grant (Biochemistry) Website

Aviad Hai (Biomedical Engineering) Website

Jeff Hardin (Zoology) Website

Katie Henzler-Wildman (Biochemistry) Website

Hazel Holden (Biochemistry) Website

Aaron Hoskins (Biochemistry) Website

Xuhui Huang (Chemistry) Website

Meyer Jackson (Neuroscience Department) Website

Mathew Jones (Neuroscience) Website

Jim Keck (Biomolecular Chemistry) Website

Robert Kirchdoerfer (Biochemistry) Website

Bob Landick (Biochemistry) Website

Ci Ji Lim (Biochemistry) Website

Megan McClean (Biomedical Engineering) Website

Matthew Merrins (Biomolecular Chemistry) Website

Jacob Notbohm (Engineering Physics) Website

Vatsan Raman (Biochemistry) Website

Ivan Rayment (Biochemistry) Website

Tom Record (Biochemistry) Website

Chad Rienstra (Biochemistry) Website

Gail Robertson (Neuroscience) Website

Phil Romero (Biochemistry) Website

Kris Saha (Biomedical Engineering) Website

David Schwartz (Chemistry) Website

Nate Sherer (Oncology) Website

Raunak Sinha (Neuroscience) Website

Melissa Skala (Biomedical Engineering) Website

Lloyd Smith (Chemistry) Website

Aussie Suzuki (Oncology) Website

Reid Van Lehn (Chemical and Biological Engineering) Website

Ophelia Venturelli (Biochemistry) Website

Amy Weeks (Biochemistry) Website

Liz Wright (Biochemistry) Website

Yongna Xing (Oncology): Website

John Yin (Chemical and Biological Engineering) Website

Martin Zanni (Chemistry) Website