GENETICS 133 — GENETICS IN THE NEWS
The science of genetics is at the heart of many issues facing our society, and as such, genetics is often in the news. Explores the underlying genetics and methodologies to gain a deeper understanding of the science behind the headlines so that we can make more informed decisions as citizens.
GENETICS 155 — FRESHMAN SEMINAR IN GENETICS
Introduction to the discipline of genetics, to the UW Laboratory of Genetics, to some of the research projects the faculty are pursuing, to resources available at UW-Madison, and to the career options open to an individual with a genetics undergraduate degree.
GENETICS 289 — HONORS INDEPENDENT STUDY
Research work for Honors students under direct guidance of a faculty member in an area encompassing Genetics. Students are responsible for arranging the work and credits with the supervising instructor.
GENETICS 299 — INDEPENDENT STUDY
Research work for students under direct guidance of a faculty member in an area encompassing Genetics. Students are responsible for arranging the work and credits with the supervising instructor.
GENETICS 375 — SPECIAL TOPICS
Specialized subject matter of current interest to undergraduate students.
GENETICS 399 — COORDINATIVE INTERNSHIP/COOPERATIVE EDUCATION
An internship under guidance of a faculty or instructional academic staff member in Genetics and internship site supervisor. Students are responsible for arranging the work and credits with the faculty or instructional academic staff member and the internship site supervisor.
GENETICS 400 — STUDY ABROAD IN GENETICS
Provides an area equivalency for courses taken on Madison Study Abroad Programs that do not equate to existing UW courses.
GENETICS 466 — PRINCIPLES OF GENETICS
Genetics in eukaryotes and prokaryotes. Includes transmission genetics, molecular genetics, evolutionary genetics, genetic engineering, and societal issues associated with genetics. Illustrative material includes bacteria, plants, insects, and vertebrates.
GENETICS 467 — GENERAL GENETICS 1
Genetics of eukaryotes and prokaryotes. Includes Mendelian genetics, probability and hypothesis testing, genetic mapping, molecular genetics, gene expression and genetic engineering. Illustrative material includes viruses, bacteria, plants, fungi, insects, and humans.
GENETICS 468 — GENERAL GENETICS 2
Genetic analysis, population genetics, evolution and quantitative genetics. Includes mutant screens, pathway analysis, mosaic analysis, reverse genetics, genomics, Hardy-Weinberg linkage equilibrium, inbreeding, genetic drift, natural selection, population structure, inheritance of complex traits, domestication and human evolution.
GENETICS 470 — BASIC CYTOLOGY AND LABORATORY PROCEDURES
A comprehensive review of cellular biology, the study of optical methods with emphasis on the light microscope and the various techniques used in preparation and staining of specimens for cytologic and histologic study.
GENETICS 471 — ADVANCED LABORATORY PROCEDURES
Preparation of non-gynecologic cytologic specimens using several different instrument methodologies. Application of universal precautions and safety in the handling of unknown biologic hazards. Introduction to histologic preparatory techniques and special staining methods.
GENETICS 520 — NEUROGENETICS
The genetic basis of nervous system development, structure, function, and dysfunction. Will emphasize both current research findings on the genetic basis of specific neurological disorders, as well as genetic methodologies and experimental approaches used in neurobiological research.
GENETICS/BIOLOGY 522 — COMMUNICATING EVOLUTIONARY BIOLOGY
Exposure to diverse topics in contemporary evolutionary biology and development of critical thinking and communication skills. Most weeks guest lecturers present their own primary research on a specialized topic in evolutionary biology. Seminars include perspectives from genetics, ecology, geoscience, zoology, botany, microbiology, systematics, molecular biology, and integrative research. Some weeks feature special topics and discussions on pedagogical, legal, outreach, or other issues in evolutionary biology. Includes thinking critically about methodology, experimental design and interpretation, and how conclusions are reached in evolutionary biology by reading primary and secondary literature, attending seminars, discussing topics with speakers and other students, and preparing a written report. The 3-credit version of the course delves deeper into communication of evolutionary biology to researchers, undergraduates, K-12 students, and the general public.
GENETICS 525 — EPIGENETICS
Introductory course in epigenetics - the layer of chemical information that sits on top of the genome - that switch genes 'on' or 'off'. Will introduce how the epigenome, in collaboration with the genome, controls versatile biological processes and cell fates. Will also cover the latest advances of how humans can control their own epigenetic destiny by lifestyle, diet, and other environmental factors.
GENETICS 527 — DEVELOPMENTAL GENETICS FOR CONSERVATION AND REGENERATION
Human-induced factors such as changes in land use and global climate are causing rapid worldwide biodiversity loss. Can modern molecular genetics contribute to species preservation? In this course, we will first explore the challenges and potential of molecular genetic methods based on biobanking, gene editing and nuclear transfer for animal biodiversity preservation. Topics covered will include: i) maternal factors and early animal development, ii) interspecies somatic cell nuclear transfer (isSCNT) and oocyte-mediated reprogramming in animal cloning, iii) developmental, phylogenetic and ecological considerations for biobanking, iv) gene editing and synthetic biology as potential tools to recapture biodiversity. Use knowledge in animal population status, developmental genetics and phylogeny to address real-life problems involving the conservation of threatened animal populations.
GENETICS 528 — BANKING ANIMAL BIODIVERSITY: INTERNATIONAL FIELD STUDY IN COSTA RICA
Study abroad course that provides an on-site educational experience where we use developmental genetics concepts to guide projects of biobanking and oocyte-mediated cloning, as a potential last-defense resort for the preservation of living species under risk of extinction. It will provide hands-on experience in current research and activities in biodiversity areas, including visits to biodiversity-rich ecosystems, on site seminars and demonstrations, biodiversity preservation activities, as well as exposure to local culture and social needs.
GENETICS 545 — GENETICS LABORATORY
Gain practical experience in classical and molecular genetic laboratory techniques using plants, animals, and fungi. Topics include complementation and linkage analysis, gene mapping, library screening, yeast and bacterial transformation, restriction analysis, PCR, sequencing, and Southern blot analysis.
GENETICS 548 — THE GENOMIC REVOLUTION
Profound advances are now possible thanks to genomic data and analysis. Introduces the structure, function, and evolution of genomes. It also outlines the realized and prospective benefits of genomic technology for human health, agriculture, and conservation.
GENETICS/HORT 550 — MOLECULAR APPROACHES FOR POTENTIAL CROP IMPROVEMENT
Introduction of basic concepts of plant molecular biology and molecular techniques in current use. Topics include: organization and regulation of plant genes, gene cloning and analysis, transformation systems for plants, and molecular techniques for crop improvement.
GENETICS 564 — GENOMICS AND PROTEOMICS
The basic principles of genomics, proteomics and bioinformatics will be taught through a semester-long project of the students choosing. Creative problem solving in science skills will be learned through a variety of active-learning techniques that include: reading of primary literature, group presentations, peer review, bioinformatic lab exercises, science communication skills (writing visualization), and creating a website. Emphasis will be placed upon how to effectively communicate science (written, oral and written). Topics include: genomic sequencing, phylogeny, domain analysis, transcriptomics, CRISPR screens, chemical genomics, quantitative proteomics and protein networks. Capstone course.
GENETICS/MD GENET 565 — HUMAN GENETICS
Principles, problems, and methods of human genetics. Surveys aspects of medical genetics, biochemical genetics, molecular genetics, cytogenetics, quantitative genetics, and variation as applied to humans.
GENETICS 566 — ADVANCED GENETICS
Principles of classical and modern genetic analysis taught through readings in the scientific literature and group projects. Capstone course.
GENETICS 567 — COMPANION RESEARCH SEMINAR
Student-led discussions on scientific, societal, and professional topics relevant to Senior research and selected original research presentations.
GENETICS 568 — THE CENTRAL NERVOUS SYSTEM
Anatomy, physiology, histology and pathology of the central nervous system and the corresponding cellular manifestations which provide diagnostic information. Cell changes related to specimen preparation. Correlation of the didactic information with the microscopic cellular patterns to provide a diagnosis.
GENETICS 569 — THE BREAST
Anatomy, histology, physiology and pathology of the breast and the corresponding cellular manifestations which provide diagnostic information. Cell changes related to specimen processing. Correlation of the didactic information with the microscopic cell patterns to provide a diagnosis.
GENETICS 570 — THE FEMALE REPRODUCTIVE SYSTEM
Anatomy, histology, physiology, and pathology of the female reproductive tract and the corresponding cellular manifestations which provide diagnostic information. Cellular changes due to therapy and specimen collection. Correlation of the didactic information with the microscopic cellular patterns to provide a diagnosis.
GENETICS 571 — CLINICAL PRACTICE I
Clinical practicum to develop diagnostic expertise involving the microscopic examination of routine gynecologic specimens (Pap smears). Observe the signout of abnormal cytologic specimens by cytopathologist staff.
GENETICS 572 — THE RESPIRATORY SYSTEM
Anatomy, histology, physiology and pathology of the respiratory tract and the corresponding cellular manifestations which provide diagnostic information. Cell changes related to specimen processing. Correlation of the didactic information with the microscopic cellular patterns to provide a diagnosis.
GENETICS 573 — THE GENITOURINARY SYSTEM
Anatomy, physiology, histology and pathology of the urinary tract and male reproductive systems and the corresponding cellular manifestations which provide diagnostic information. Cell changes related to specimen processing. Correlation of didactic information with microscopic cell patterns to provide a diagnosis.
GENETICS 574 — THE GASTROINTESTINAL SYSTEM
Anatomy, histology, physiology and pathology of the gastrointestinal system and the corresponding cellular manifestations which provide diagnostic information. Cell changes related to specimen processing. Correlation of the didactic information with the microscopic cellular patterns to provide a diagnosis.
GENETICS 575 — MISCELLANEOUS SYSTEMS
Anatomy, histology, physiology and pathology of skin, thyroid, lymph nodes and other sites and the corresponding celluular manifestations which provide diagnostic information. Emphasis on specimen collection by fine needle aspiration. Correlation of the didactic information with the microscopic cellular patterns to provide a diagnosis.
GENETICS 576 — EFFUSIONS
Anatomy, physiology, histology and pathology of the body cavities. Cytologic manifestations which provide diagnostic information. Cell changes related to specimen processing. Correlation of the didactic information with the microscopic cellular patterns to provide a diagnosis.
GENETICS 577 — APPLIED CYTOLOGY I
Written and practical application of the comprehensive body of knowledge to all aspects of preparation, evaluation, correlation and diagnosis of cytologic speciments.
GENETICS 578 — APPLIED CYTOLOGY II
Written and practical application of the advanced comprehensive body of knowledge to all aspects of preparation, evaluation, correlation and diagnosis of cytologic specimens. Practice in nationally offered cytologic examinations.
GENETICS 588 — IMMUNOGENETICS
Immunogenetics focuses on the unique genetic phenomena that occur in lymphocytes during development and response to stimuli. It pays particular attention to the processes of adaptive antigen receptor development and maturation, major histocompatibility complex molecule polygeny and polymorphism in the context of current real-life challenges (e.g. COVID-19, influenza, and HIV), immunological evolution, epigenetics associated with autoimmunity, sex differences in immune responses, and some genetic processes involved in cancer of white blood cells. Ultimately, the genetic mechanisms that drive the immunological and clinical differences observed between individuals when confronted with the same challenge will be examined, and explored through the primary and secondary research literature in order to strengthen scientific literacy.
GENETICS 605 — CLINICAL CASES IN MEDICAL GENETICS
The use of genetics in medicine has experienced significant growth over the past 50 years, identifying risk genes, and devising diagnostic tests and therapies based on this knowledge for specific clinical disorders such as cystic fibrosis, achondroplasia, and Retts syndrome. MDs and biomedical scientists from UW Hospital and Clinics, the School of Medicine and Public Health, and other UW units will present lectures in this field followed by question-answers sessions. Other class sessions will be devoted to student presentations and open discussion of research literature.
GENETICS/BIOCHEM/MICROBIO 612 — PROKARYOTIC MOLECULAR BIOLOGY
Molecular basis of bacterial physiology and genetics with emphasis on molecular mechanisms; topics include nucleic acid-protein interactions, transcription, translation, replication, recombination, regulation of gene expression.
GENETICS/AGRONOMY/AN SCI/HORT 615 — GENETIC MAPPING
Computing-intensive course to prepare students for genetic mapping research; linkage analysis and QTL mapping in designed crosses; linkage disequilibrium and association analysis (GWAS). Recommended preparation is undergraduate courses in genetics and statistics and prior experience writing R scripts (such as module 1 of STAT 327).
GENETICS/BIOCHEM/MD GENET 620 — EUKARYOTIC MOLECULAR BIOLOGY
Focuses on the basic molecular mechanisms that regulate DNA, RNA, and protein metabolism in eukaryotic organisms.
GENETICS/ENTOM/ZOOLOGY 624 — MOLECULAR ECOLOGY
Basic principles of molecular ecology. Lecture topics include population genetics, molecular phylogenetics, rates and patterns of evolution, genome evolution, and molecular ecology.
GENETICS/CHEM 626 — GENOMIC SCIENCE
Brings cutting-edge topics in the genomic sciences into the reach of those in chemistry, biology, engineering, computer science statistics fields. Enables biologically-oriented students to deal with advances in analytical science so that they may incorporate new genomic science concepts into their own scientific repertoires.
GENETICS 627 — ANIMAL DEVELOPMENTAL GENETICS
Advanced genetics course focusing on genetic mechanisms of animal embryonic development, with particular emphasis on central molecular circuitries that control development and genetic analytical tools used to reveal them. Address topics including maternal and epigenetic inheritance, the egg-to-embryo transition, pattern formation, organogenesis, coordination of cellular and molecular mechanisms, and animal models of human congenital disorders.
GENETICS/BIOCHEM 631 — PLANT GENETICS AND DEVELOPMENT
Covers the basic concepts of genetics and genomics as applied to plants and their development, including discussions on breeding systems (modes of reproduction, sex determination, self incompatibility and crossing barriers), linkage analysis, genome structure and function (structure, function and evolution of nuclear and organellar chromosomes; haploidy and polyploidy; expression regulation and epigenetics), along with a description of current methodologies used in the analysis of these processes within the context of plant development. The objective is to instigate a broader knowledge and understanding of the principles and methodologies used in plant genetics and their applications in investigations of the molecular mechanisms that modulate plant development.
GENETICS 633 — POPULATION GENETICS
Population genetics, aimed at preparing students to initiate research in this field. Explore how genetic variation is influenced by mutation and recombination, population size changes and migration, and natural selection for or against new mutations.
GENETICS/MD GENET/POP HLTH 636 — PUBLIC HEALTH GENOMICS
Provides an introduction to public health genomics through a review of fundamental principles of genetics, the use of genetic information in clinical and research settings, and its implications for disease management and prevention, and health promotion. Explores policies that guide public health and discusses current ethical, legal, and social implications of these policies.
GENETICS/BOTANY/M M & I/PL PATH 655 — BIOLOGY AND GENETICS OF FUNGI
Fungal genetics, genomics, and physiology using plant pathogenic fungi and the genetic models Aspergillus nidulans and Neurospora crassa as model systems to explore the current knowledge of fungal genetics and plant/fungal interactions.
GENETICS/MD GENET 662 — CANCER GENETICS
Cancer remains one of the most difficult health issues facing our society. There is hope in the horizon due to an increasing understanding of both genetic and epigenetic alterations in cancer. In particular, DNA sequencing of human cancers is becoming more common in major health care centers, and there is expectation that this technology will allow for personalized medicine. Thus, there has been a rapid increase in this knowledge over the last decade. Become aware of the current major issues in cancer research and critically evaluate the cancer genetics literature.
GENETICS 670 — SEMINAR IN CLINICAL CYTOGENETICS
Overview of the basic features of chromosome structure and behavior including karyotyping clinical correlates of numerical and structural chromosome aberrations, sex chromosome abnormalities, breakage syndromes and the chromosomal changes associated with the development of cancer.
GENETICS 671 — ADVANCED CLINICAL PRACTICE
Clinical practicum to develop diagnostic expertise of cytologic specimens. Examine challenging cases with emphasis on diagnostic pitfalls. Observe patient clinics related to cytologic specimen collection. Participate at clinical experiences in fine needle aspiration, histology, and a private cytology laboratory.
GENETICS 672 — SEMINAR IN LABORATORY OPERATIONS AND QUALITY CONTROL
Review the fundamentals of basic administrative functions and regulatory requirements including planning, organizing, supervising and controlling business management, record keeping, data processing and laboratory safety. Quality assurance procedures necessary for obtaining, processing, diagnosing and reporting cytologic specimens.
GENETICS 673 — SEMINAR IN CLINICAL CYTOLOGY
Preparation of a case study or clinical topic of choice by each student to present to a peer professional group of cytology staff and medical faculty. Preparation of a referenced scientific term paper or participation in an approved research or class project pertaining to cliniccal cytology.
GENETICS/MD GENET 677 — ADVANCED TOPICS IN GENETICS
Contents vary; consideration of subjects not included in the curriculum.
GENETICS 681 — SENIOR HONORS THESIS
Individual study for majors completing theses for Honors degrees as arranged with a faculty member.
GENETICS 682 — SENIOR HONORS THESIS
Individual study for majors completing theses for Honors degrees as arranged with a faculty member.
GENETICS 699 — SPECIAL PROBLEMS
Individual advanced work in an area of Genetics under the direct guidance of a faculty member.
GENETICS 701 — ADVANCED GENETICS
First semester of professional level training in genetic mechanisms and analysis as applied to genetic transmission, gene expression, forward and reverse genetics, molecular genetics, genonmics, developmental genetics, and epigenetics.
GENETICS 702 — ADVANCED GENETICS II
Second of semester of professional level training in genetic mechanisms and analysis as applied to genetic transmission, gene expression, forward and revese genetics, molecular genetics, genonmics, developmental genetics, and epigenetics.
GENETICS/MD GENET 707 — GENETICS OF DEVELOPMENT
A research-level analysis of the current status of the investigation of processes controlling differential gene activity and cellular behavior. The major emphasis is genetic. In successive years, the focus moves from the gene to the cell to the organism.
GENETICS/MD GENET 708 — METHODS AND LOGIC IN GENETIC ANALYSIS
Contemporary issues in genetic, developmental, cell, and molecular biology are addressed in a discussion format. Invited speakers give research lectures and reading material is taken from the primary literature. The discussion focuses on evaluating genetic approaches to biological problems.
GENETICS/CRB 710 — DEVELOPMENTAL GENETICS
Covers a broad range of topics in animal development, with an emphasis on molecular mechanisms. Focuses on common themes, with the goal of understanding and analyzing current research in developmental biology and genetics.
GENETICS/BOTANY/ENTOM/ZOOLOGY 820 — FOUNDATIONS OF EVOLUTION
Explore some of the most important themes and debates that have permeated evolutionary biology over the last 50 years. Read key papers related to each controversial topic, debate the pros and cons of competing viewpoints, and reflect on the relevance of the issue to contemporary evolutionary biology.
GENETICS/BIOCHEM/BOTANY 840 — REGULATORY MECHANISMS IN PLANT DEVELOPMENT
Molecular mechanisms whereby endogenous and environmental regulatory factors control development; emphasis on stimulus perception and primary events in the signal chain leading to modulated gene expression and cellular development.
GENETICS/AN SCI/POP HLTH 849 — GENETIC EPIDEMIOLOGY
This course will provide an introduction to genetic epidemiology. Topics will include a general overview of genetics and Mendelian and complex inheritance, as well as various elements of study design, including participant ascertainment; phenotype definition; biologic sample selection; genotyping, sequencing, and quality control; measurement of covariates, and choice of analytic methods. We will briefly discuss some of the original study designs and then focus on current study designs for the remainder of the class. Additional emerging topics will be briefly touched upon. Students will complete short homework assignments to enforce concepts learned during lectures, discuss journal articles, and prepare a very short grant application for the mid-term project. In the final weeks of class, students will work together to analyze data from a real genetic study, prepare tables, interpret the findings, and present their project to their peers.
GENETICS 875 — SPECIAL TOPICS
Special topics of current interest to graduate students.
GENETICS 885 — ADVANCED GENOMIC AND PROTEOMIC ANALYSIS
With the availability of genome sequences and high-throughput techniques, organismal physiology can now be examined on a global scale by monitoring the behavior of all genes or proteins in a single experiment. This course will present modern techniques in genomics and proteomics, with particular focus on analyzing the data generated by these techniques. Course material will cover genomic sequencing, comparative sequence analysis, phylogeny construction and phylogenomics, transcription factor motif discovery, DNA microarray analysis, techniques in mass spectrometry, proteomic screening methods, and protein-interaction network analysis. In addition to lecture time, the course includes computer lab where students get hands-on experience analyzing genomic and proteomic datasets. Students should have coursework in general statistics and intermediate or advanced genetics.
GENETICS/B M E/B M I/BIOCHEM/CBE/COMP SCI 915 — COMPUTATION AND INFORMATICS IN BIOLOGY AND MEDICINE
Participants and outside speakers will discuss current research in computation and informatics in biology and medicine. This seminar is required of all CIBM program trainees.
GENETICS/AN SCI/DY SCI 951 — SEMINAR IN ANIMAL BREEDING
GENETICS/AGRONOMY/HORT 957 — SEMINAR-PLANT BREEDING
Graduate seminar in Plant Breeding Plant Genetics (PBPG) that requires students to give oral scientific presentations on topics chosen by the instructors and/or the student¿s thesis research. This seminar is coordinated by PBPG faculty on a rotating basis.
GENETICS 990 — RESEARCH
Independent laboratory research in preparation of a graduate thesis under supervision of a faculty member.
GENETICS 993 — SEMINAR IN GENETICS
Various aspects of genetics: Drosophila, maize, immunogenetics, developmental genetics, or other special topics.