Molecular and Environmental Toxicology Center (M&ENVTOX)

M&ENVTOX/ONCOLOGY/PHM SCI/PHMCOL-M/POP HLTH 625 — TOXICOLOGY I

3 credits.

Basic principles of toxicology and biochemical mechanisms of toxicity in mammalian species and man. Correlation between morphological and functional changes caused by toxicants in different organs of the body.

Requisites: (BIOCHEM 501 or 508) and (ANAT&PHY 335, 435, or (BIOCORE 485 and 486)) and PATH 404; or graduate/professional standing

Course Designation: Breadth - Biological Sci. Counts toward the Natural Sci req
Level - Advanced
L&S Credit - Counts as Liberal Arts and Science credit in L&S
Grad 50% - Counts toward 50% graduate coursework requirement

Repeatable for Credit: No

Last Taught: Fall 2025

Learning Outcomes: 1. Discuss the physiology and pathology of toxicology, understanding the basicfundamentals of toxicology and toxic agents
Audience: Both Grad & Undergrad

2. Demonstrate metabolism and breakdown of toxicants using a given dataset
Audience: Both Grad & Undergrad

3. Recognize various experimental models to obtain scientific results
Audience: Both Grad & Undergrad

4. Implement knowledge to design experiments applicable to one’s own research
Audience: Both Grad & Undergrad

5. Critique an example of toxicology in media and develop a presentation of this example
Audience: Both Grad & Undergrad

6. Explore new areas to assist in career development via journal club
Audience: Graduate

M&ENVTOX/PATH/PHM SCI/PHMCOL-M/POP HLTH 626 — TOXICOLOGY II

3 credits.

Survey of the basic methods and fundamental biochemical mechanisms of toxicity. Toxicity in mammalian organ systems, techniques for evaluating toxicity, as well as mechanisms of species specificity, and environmental interactions (with toxicant examples) are presented.

Requisites: POP HLTH/M&ENVTOX/ONCOLOGY/PHM SCI/PHMCOL-M 625

Repeatable for Credit: No

Last Taught: Spring 2026

Learning Outcomes: 1. Explain and identify the effects of toxicants on specific organs within the human body
Audience: Both Grad & Undergrad

2. Demonstrate metabolism and reactions of toxicants within organ systems using a given dataset
Audience: Both Grad & Undergrad

3. Classify different means of risk assessment and the conceptual rationale behind these methods
Audience: Both Grad & Undergrad

4. Implement knowledge to design experiments applicable to one's own research
Audience: Both Grad & Undergrad

5. Relate specific organ concepts with conceptual examples from M&ENVTOX 625 to enhance scientific understanding
Audience: Undergraduate

6. Appraise concepts to research to identify future research concepts.
Audience: Graduate

M&ENVTOX/CIV ENGR/SOIL SCI 631 — TOXICANTS IN THE ENVIRONMENT: SOURCES, DISTRIBUTION, FATE, & EFFECTS

3 credits.

Nature, sources, distribution, and fate of contaminants in air, water, soil, and food and potential for harmful exposure.

Requisites: (CHEM 104, 109, or 116) and (MATH 211, 217, or 221) and (PHYSICS 104, 202, 208, or 248), or graduate/professional standing

Repeatable for Credit: No

Last Taught: Spring 2026

Learning Outcomes: 1. Describe how the physicochemical properties of an organic chemical and equilibrium and kinetic principles influence the distribution of the chemical in the environment
Audience: Both Grad & Undergrad

2. Estimate the physico-chemical properties of organic compounds using linear free energy relationships
Audience: Both Grad & Undergrad

3. Predict the behavior of hazardous organic chemicals in the environment
Audience: Both Grad & Undergrad

4. Derive and use equilibrium and kinetic box models for determining the fate of organic pollutants in the environment
Audience: Graduate

M&ENVTOX 699 — SPECIAL PROBLEMS

1-3 credits.

Directed study projects as arranged with instructor.

Requisites: Consent of instructor

Course Designation: Level - Advanced
L&S Credit - Counts as Liberal Arts and Science credit in L&S

Repeatable for Credit: Yes, unlimited number of completions

Last Taught: Summer 2022

Learning Outcomes: 1. Apply concepts learned in coursework to real life situations
Audience: Undergraduate

2. Read and effectively search scientific literature
Audience: Undergraduate

3. Develop critical, analytical, and independent thinking skills
Audience: Undergraduate

M&ENVTOX 800 — SEMINAR

1 credit.

Current research in environmental toxicology and pathology and other topics of interest and importance to environmental toxicologists.

Requisites: Graduate/professional standing

Course Designation: Grad 50% - Counts toward 50% graduate coursework requirement

Repeatable for Credit: Yes, unlimited number of completions

Last Taught: Spring 2026

Learning Outcomes: 1. Design, develop, and present research to audiences of peers within and outside of research area.
Audience: Graduate

2. Evaluate data and appraise presentations.
Audience: Graduate

3. Recognize opportunities in research tools and professional development to further career trajectory.
Audience: Graduate

4. Synthesize data from others to apply towards own research.
Audience: Graduate

M&ENVTOX 801 — SCIENTIFIC COMMUNICATION IN MOLECULAR & ENVIRONMENTAL TOXICOLOGY

2 credits.

Provides an overview of scientific communication; specifically, students will be exposed to the various methods of communicating their science including articles, proposals, presentations / lectures, and posters. Strategies will demonstrate best practices for each method and enable students to critically define what sets apart good examples from poor. Classroom discussions allow for comprehension of these means. Assignments are designed to familiarize the students with these methods. Students will have classroom instruction and the opportunity to learn from peer mentors as well as laboratory directors on different preferences and approaches to science communication.

Requisites: Graduate/professional standing

Course Designation: Grad 50% - Counts toward 50% graduate coursework requirement

Repeatable for Credit: No

Last Taught: Spring 2026

Learning Outcomes: 1. Identify best practices when communicating science in multiple forms
Audience: Graduate

2. Synthesize data to create a coherent hypothesis for research question
Audience: Graduate

3. Analyze sources and approaches necessary for a scientific literature review
Audience: Graduate

4. Integrate knowledge to critique a scientific publication that is under review
Audience: Graduate

5. Produce preliminary sections for use in a scientific manuscript
Audience: Graduate

6. Evaluate how to critique scientific proposals and compose meaningful feedback
Audience: Graduate

7. Produce a document for use as a preliminary exam and / or fellowship proposal
Audience: Graduate

8. Organize preliminary data generated in mentored laboratory into a research poster that is both appealing and informative
Audience: Graduate

9. Create a PowerPoint presentation, which will teach students and classmates about a scientific tool or otherwise professional development topic, whose knowledge will be beneficial to students as they advance their careers
Audience: Graduate

10. Produce a Teaching Philosophy statement to start a professional teaching portfolio
Audience: Graduate

M&ENVTOX 990 — RESEARCH

1-9 credits.

Independent research and writing for graduate students under the supervision of a faculty member.

Requisites: Consent of instructor

Course Designation: Grad 50% - Counts toward 50% graduate coursework requirement

Repeatable for Credit: Yes, unlimited number of completions

Last Taught: Spring 2026

Learning Outcomes: 1. Exhibit a broad understanding of general toxicology principles
Audience: Graduate

2. Conduct independent research using a variety of approaches
Audience: Graduate

3. Think critically to address research challenges
Audience: Graduate

4. Exhibit and foster professional and ethical conduct in their research
Audience: Graduate

5. Collaborate with other investigators within or outside of the thesis lab
Audience: Graduate