SoPharm_pharmacy-pharmaceuticalsci-bs

The Division of Pharmaceutical Sciences at the School of Pharmacy offers the doctor of philosophy (Ph.D.) degree in pharmaceutical sciences. The program provides a rigorous background in a range of scientific disciplines that are critical to the success of the next generation of pharmaceutical scientists. The program’s interdisciplinary training combines pharmaceutically relevant aspects of classical disciplines such as chemistry, biology, and engineering. Students earn a Ph.D. in Pharmaceutical Sciences, concentrating in one of three research cores: Drug Discovery, Drug Action, or Drug Delivery. Extensive communication and collaboration occur between these cores, mirroring the importance of interdisciplinary research teams in the pharmaceutical field.

Research in Drug Discovery focuses on areas related to medicinal chemistry, such as small molecule development, natural products isolation and characterization, organic synthesis, chemical biology, and rational drug design.

Drug Action focuses on areas related to pharmacology, toxicology, cellular differentiation, development, and disease.  Interests include the impact of drugs and toxins on biological systems, mechanisms of normal biology, and mechanisms of disease. These are studied at the cellular, genetic, molecular, and biochemical levels using diverse model systems.

Drug Delivery (pharmaceutics) emphasizes principles in physical chemistry and drug transport, aiming for advances in formulation, drug targeting, and multi-modal therapy. Delivery research includes the solid-state chemistry of drugs, nano-pharmacy, biocompatibility, molecular recognition, computational chemistry, pharmacokinetics, and molecular imaging.

The UW–Madison Pharmaceutical Sciences Division has been recognized for its research productivity, extramural funding support, publication record and teaching.  The School of Pharmacy is housed in Rennebohm Hall, a seven-story, state-of-the-art facility.

Postgraduate Information

Recent program graduates have found employment in a variety of industrial settings or in prestigious postdoctoral academic research labs.  Opportunities in research and development roles for pharmaceutical, chemical, biotechnology and other innovation-minded companies are a common postgraduate path; some graduates eventually achieve faculty positions at small colleges or at larger research institutions. By partnering with other units on campus, the program has increased career services such that students can sharpen their professional and communication skills and reach a larger network of potential employers. The program graduated 36 Ph.D.s from 2012 to 2016; over 90 percent of these recent alumni were professionally placed (i.e., working in the field) within six months of graduation. For more information on first professional placement following graduation, see employers of recent PharmSci graduates on the program website. Faculty and the school's graduate programs coordinator can be consulted for specific career information (both initial placement and longer-term employment information regarding Ph.D. alumni).

Facilities

The pharmaceutical sciences division is housed in Rennebohm Hall, a seven-story, state-of-the-art facility that opened in 2001 and offers 120,000 assignable square feet. The pharmaceutical sciences division comprises floors 4 to 7 of  Rennebohm Hall and features 34 laboratories; affiliate Pharmaceutical Sciences graduate faculty are housed at other campus buildings . Located on the northwest edge of campus, Rennebohm Hall is in close proximity to the Health Sciences Learning Center (home of the UW School of Medicine and Public Health), UW Hospital and Clinics, the UW Institute for Clinical and Translational Research (ICTR), the Waisman Center, the Wisconsin Institutes for Medical Research (WIMR), the School of Veterinary Medicine, the School of Nursing, and Ebling Library for the Health Sciences. Many researchers affiliated with Wisconsin's Carbone Comprehensive Cancer Center work within these adjacent facilities.

Exceptional research facilities and equipment are highlighted by the school's Analytical Instrumentation Center (AIC), comprising mass spectrometry, nuclear magnetic resonance, spectroscopy, and spectrophotometry facilities. The AIC's high-tech instrumentation expedites the isolation and full structural elucidation of small molecules. These chemical entities can be subsequently evaluated via high throughput screening toward lead generation, or specifically utilized to prove novel biological phenomenon toward in-depth mechanistic study. The division offers centralized facilities for computer-aided drug and catalyst design, real-time PCR, gene array detectors, gas chromatographs, high-pressure liquid chromatographs, cell culture, ultra-centrifuges, scintallation counters, and animal care for a variety of species.

The school's Lenor Zeeh Pharmaceutical Experiment Station is a not-for-profit, self-sustaining center of expertise serving faculty researchers across the UW–Madison campus as well as private-sector drug product development. The station provides laboratory services related to compound physical/chemical characterization and basic formulation development to support preclinical development of promising drug candidates and other unmet pharmaceutical-related needs. Pharmaceutical sciences graduate students are eligible to participate in summer internships at the station. Pharmaceutical sciences also houses the university's Medicinal Chemistry Center (MCC), whose mission is to provide drug discovery expertise to the UW medical community and drive translational research at UW–Madison through designing and synthesizing novel small molecule based therapeutics.  Pharmaceutical sciences faculty direct the MCC.

Accepted students commonly have strong scientific backgrounds, a passion for research, and significant laboratory experience. Students with undergraduate degrees in the physical or biological sciences, engineering, pharmacy, and related fields are encouraged to apply.  Students who have earned masters degrees are also welcomed to apply, but a masters degree is not a requirement.  One may apply directly to the Pharmaceutical Sciences Ph.D. program with a bachelor's degree background (as long as a bachelor's degree would be completed by the time one would begin graduate studies).

Please see admissions on the program website for the application deadline and required supplemental materials.  Related links describe frequently-asked admissions questions, selection criteria, and typical pharmaceutical research paths for various undergraduate majors.

Graduate School Admissions

Graduate admissions is a two-step process between academic degree programs and the Graduate School. Applicants must meet requirements of both the program(s) and the Graduate School. Once you have researched the graduate program(s) you are interested in, apply online.  

Graduate School Resources

Resources to help you afford graduate study might include assistantships, fellowships, traineeships, and financial aid. Further funding information is available from the Graduate School. Be sure to check with your program for individual policies and processes related to funding.

Program Resources

Financial support is provided to all graduate students in Pharmaceutical Sciences through a combined mechanism of fellowships, teaching assistantships, research assistantships, and project assistantships. Funding packages for first-year students in the Ph.D. program are provided by the School of Pharmacy and consist of a mixture of fellowships and/or teaching assistant support. In addition, first-year students earn $1500 in flexible funds to aid in the transition to Madison. After the first academic year, students are supported by their thesis advisor through research assistantship or teaching assistantship appointments. All students receive a stipend (the recommended minimum level for students in the division is $25,000 for 2017–18, a figure that is adjusted annually), full tuition remission (waiver), and most of the cost of reasonably priced, comprehensive health insurance for the duration of their Ph.D. studies, if they retain good academic standing and a faculty advisor.  For more details, see this program-specific funding page

Travel grants are available annually; the program has funding to provide seven graduate students with travel grants each year.  Students who are presenting at scientific conferences are preferred applicants; awards range from $1000–$1500.  Most students are additionally supported in scientific conference travel via faculty funds.

Minimum Graduate School Requirements

Review the Graduate School minimum academic progress and degree requirements, in addition to the program requirements listed below.

Major Requirements

MODE OF INSTRUCTION

Face to Face Evening/Weekend Online Hybrid Accelerated
Yes No No No No

Mode of Instruction Definitions

CURRICULAR REQUIREMENTS

Minimum Credit Requirement 51 credits
Minimum Residence Credit Requirement 32 credits
Minimum Graduate Coursework Requirement Half of degree coursework (26 credits out of 51 total credits) must be completed graduate-level coursework; courses with the Graduate Level Coursework attribute are identified and searchable in the university's Course Guide (http://my.wisc.edu/CourseGuideRedirect/BrowseByTitle).
Overall Graduate GPA Requirement 3.00 GPA required.
Other Grade Requirements Candidates may be dropped from the program if they receive more than 7 credits of grades at the BC level or lower. This applies to formal courses and research credits.
Assessments and Examinations The preliminary examination is expected to be completed before the beginning of the third year of graduate study. For specifics regarding the preliminary examination’s structure and requirements, see Preliminary Examination in the PSD Student Handbook (https://pharmacy.wisc.edu/graduate-handbook-pharmaceutical-sciences/preliminary-examination/).

A final oral defense of the dissertation is required; for more on the dissertation defense, see Ph.D. Thesis Defense in the PSD Student Handbook (https://pharmacy.wisc.edu/graduate-handbook-pharmaceutical-sciences/phd-thesis-defense/).
Language Requirements There are no language requirements in the Pharmaceutical Sciences Ph.D. program.
Doctoral Minor/Breadth Requirements No doctoral minor is required.

Required COURSES

PHM SCI 780 Principles of Pharmaceutical Sciences3
Select at least two of the following core courses:6
Pharmacokinetics
Natural Product Synthesis, Biosynthesis and Drug Discovery
Cellular Signal Transduction Mechanisms
Research ethics/responsible conduct of research course1
Three additional credits from the Drug Action, Drug Delivery, or Drug Discovery elective lists are required (courses meeting this requirement are listed in the Pharmaceutical Sciences Graduate Handbook)3
Seminar & Research
Pharmaceutical Sciences Seminar (required every fall term during enrollment as a graduate student in the program) 1
Pharmaceutical Sciences Seminar (required every spring during enrollment as a graduate student in the program) 1
Research 2

To enhance a required core curriculum, an individualized course of study is planned with a faculty advisor. Faculty advisors have the option to require additional courses beyond the minimum requirements listed above.

Graduate School Policies

The Graduate School’s Academic Policies and Procedures provide essential information regarding general university policies. Program authority to set degree policies beyond the minimum required by the Graduate School lies with the degree program faculty. Policies set by the academic degree program can be found below.

Major-Specific Policies

Graduate Program Handbook

The Graduate Program Handbook is the repository for all of the program's policies and requirements.

Prior Coursework

Graduate Work from Other Institutions

With program approval, students are allowed to count no more than 15 credits of graduate coursework from other institutions (the student must have graduate student status on the other institution’s transcript at the time the courses were taken). Coursework should be presented to the SoP graduate dean in the first semester of enrollment for consideration. Coursework earned ten years or more prior to admission to a doctoral degree is not allowed to satisfy requirements.

UW–Madison Undergraduate

With approval of the School of Pharmacy’s graduate studies dean, students are allowed to count no more than 7 credits of UW–Madison courses numbered 500 or above (earned as a UW–Madison undergraduate) toward the Ph.D.  Coursework should be presented to the SoP graduate dean in the first semester of enrollment for consideration. Coursework earned ten years or more prior to admission to a doctoral degree is not allowed to satisfy requirements.

UW–Madison University Special

With program approval, students are allowed to count no more than 15 credits of coursework numbered 500 or above taken as a UW–Madison special student toward the Ph.D. Coursework should be presented to the SoP graduate dean in the first semester of enrollment for consideration. Coursework earned ten years or more prior to admission to a doctoral degree is not allowed to satisfy requirements.

ProbatioN

A semester GPA below 3.0 will result in the student being placed on academic probation. If a semester GPA of 3.0 is not attained during the subsequent semester of full time enrollment (or 12 credits of enrollment if enrolled part-time) the student may be dismissed from the program or allowed to continue for one additional semester based on advisor appeal to the Graduate School.

ADVISOR / COMMITTEE

All students in the Ph.D. program are required to have a major professor/advisor through the duration of their studies. Typically a permanent advisor is found by the end of one’s first semester.

All students are required to conduct an annual progress meeting with their thesis committee each year. The meeting should be completed by the end of August of each consecutive academic year. In years where the preliminary exam or the Ph.D. thesis defense are scheduled, these events may substitute for the annual progress meeting. For details on the annual progress report, see the PSD Student Handbook. For details on the composition requirements of the Ph.D. preliminary exam/thesis committee, see Thesis Committee in the PSD Student Handbook.

CREDITS PER TERM ALLOWED

15 credits

Time Constraints

It is expected that Ph.D. major course requirements will be completed by the end of year two in the program.

A candidate for a doctoral degree who fails to take the final oral examination and deposit the dissertation within five years after passing the preliminary examination may be required to take another preliminary examination and to be admitted to candidacy a second time.

Other

First-year students are typically offered fellowships and School of Pharmacy teaching assistantships in their initial two semesters. Funding as research assistants is assumed by the student's principal investigator/thesis advisor in the first summer. Subsequently (year 2 and beyond), students are funded by RA-ships, TA-ships and via other extramural funding (fellowship) support.

Graduate School Resources

Take advantage of the Graduate School's professional development resources to build skills, thrive academically, and launch your career. 

1. Demonstrate critical knowledge and in-depth understanding of principles in the student's area of expertise.

2. Identify important research questions, formulate testable hypotheses, and design experiments to test those hypotheses.

3. Conduct original research that contributes to the student's field of study.

4. Communicate scientific knowledge and research results effectively to a range of audiences.

5. Demonstrates breadth within their learning experiences.

6. Advances contributions of the field of study to society.

7. Apply ethical principles in conducting scientific research.

A list of pharmaceutical sciences graduate faculty and their respective areas of research specialization is available from the division website and related links. The Pharmaceutical Sciences Graduate Program has educated generations of scientists for challenging positions in industry, academia, and government.